ameenah nadeem



Ameenah khan, Imran Masoud Qasmi ,Tariq mehmood mirza, Khadija tul Kubra

Department of Radiology, CMH,Lahore





BACKGROUND:  Polycystic ovarian syndrome is a common endocrine disorder of females of reproductive age group. Recent studies have shown that changes in Doppler indices of ovarian arteries  in patients of PCOS are much more marked than changes in morphology of ovary and uterus.

OBJECTIVE : To determine frequency  of  deranged ovarian artery Doppler indices in patients of PCOS  in the form of percentage


STUDY DESIGN: Descriptive cross sectional study.




DURATION OF STUDY : Nov 2018 to April 2019



 Total 205 women aged between 18-40 years presenting with PCOS were included. Transvaginal  Doppler ultrasound was performed to determine Pulsatility and Resistive indices of ovarian artery which were labelled deranged if above or below the normal range. PI ( range: 2.01to 4.30 ) and  RI (range: 0.80 to 0.95 ). Data was stratified for age, BMI and duration of PCOS.





The Pulsatility index ranged from 2.01 to 4.27. Resistive index ranged from 0.80 to 0.94. Ovarian artery Doppler indices were deranged in 175 (85.4%) women with PCOS. The mean age of the patients was 27.2±5.9 years while the mean duration of PCOS was 18.4±7.1 months. The BMI of patients ranged from 20.8 Kg/m2 to 34.0 Kg/m2 with a mean of 26.9±3.9 Kg/m2. 33.6% of obese women had deranged ovarian artery Doppler indices.



In this study, we observed that ovarian artery Doppler indices were deranged in a significant proportion of women with PCOS which suggests potential role of Doppler indices in the diagnostic workup of women with suspicion of PCOS.


KEY WORDS: Polycystic Ovarian Syndrome, Ultrasound Doppler, Pulsatility Index, Resistive Index   

Full Text:




Sirmans SM, Pate KA. Epidemiology & management of PCOS .Clin Epidemiol 2014;6:1

Rosenfield RL, Ehrmann DA. The pathogenesis of polycystic ovary syndrome (PCOS): the hypothesis of PCOS as functional ovarian hyperandrogenism revisited. Endocr Rev 2016;37(5):467-520.

Ehrmann DA. Polycystic ovary syndrome. N Engl J Med 2005;352(12):1223-36.

Schmid J, Kirchengast S, Vytiska-Binstorfer E, Huber J. Infertility caused by PCOS--health-related quality of life among Austrian and Moslem immigrant women in Austria. Hum Reprod 2004;19(10):2251-7.

Teede H, Deeks A, Moran L. Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan. BMC Med 2010;30(8):41.

Boyle J, Teede HJ. Polycystic ovary syndrome - an update. Aust Fam Physician 2012;41(10):752-6.

Akram M, Roohi N. Endocrine correlates of polycystic ovarian syndrome in Pakistani women. J Coll Physicians Surg Pak 2015;25(1):22-6.

Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to PCOS Fertil Steril 2004;81(1):19-25.

Artini PG, Di Berardino OM, Simi G, Papini F, Ruggiero M, Monteleone P, et al. Best methods for identification and treatment of PCOS. Minerva Ginecol 2010;62(1)

Battaglia C. The role of USG and Doppler analysis in diagnosis of PCOS Obstet Gynecol 2003;22:225-32.

Pellizzari P, Esposito C, Siliotti F, Marchiori S, Gangemi M. Colour Doppler analysis of ovarian and uterine arteries in women with hypoestrogenic amenorrhoea. Hum Reprod 2002;17(12):3208-12.

Bano A, Tariq A, Rehman AU. Diagnosis of PCOS on Doppler based resistive and pulsatility index. J Rawal Med Coll 2016;20(4):305-8.

Wahab S, Farnaz, Karim R. Role of metformin in polycystic ovarian syndrome. J Postgrad Med Inst 2013;27(2):179-83.

Usmani A, Rehman R, Akhtar Z. Association of BMI and dietary habits with ovarian and uterine morphology with PCOS. J Postgrad Med Inst 2014;28(2):133-8.

Chaudhari AP, Mazumdar K, Mehta PD. Anxiety, depression, and quality of life in women with polycystic ovarian syndrome. Indian J Psychol Med 2018;40(3):239-46.

Kumar A, Barki S, Raghav V, Chaturvedi A, Kumar KVSH. Correlation of Vitamin D with metabolic parameters in polycystic ovarian syndrome. J Family Med Prim Care 2017;6(1):115-9.

Qazi II, Qazi AT, Ijaz F, Jawed S, Aftab RK, Qazi SR. Relationship of obesity with insulin resistance in polycystic ovarian syndrome. Pak J Physiol 2018;14(3):46-9.

Gupta V, Sharma S, Raina SK, Bedi GK. Clinical and biochemical correlates of PCOS: a case–control study from a tertiary care center in North India. J Sci Soc 2018;45(1)

Wagan F. Polycystic ovarian syndrome: response to metformin therapy. Pak J Med Health Sci 2011;27(5):11-24.

Raja SA, Prasad PVS, Kaviarasan PK. Prevalence and pattern of PCOS in women presenting with acne, a hospital based prospective observational study. Int J Res Med Sci 2018;6:899-903.

Maciołek-Blewniewska G, Kozarzewski M, Szpakowski M, Pertyński T, Nowak M. [The evaluation of blood flow in uterine arteries in girls with PCOS by transvaginal color Doppler ultrasonography]. Ginekol Pol 1999;70(5):412-7.

Aleem FA, Predanic M. Transvaginal color Doppler determination of the ovarian and uterine blood flow characteristics in polycystic ovary disease. Fertil Steril 1996;65(3):510-6.


  • There are currently no refbacks.

© Copyright PJR 2008-