DIAGNOSTIC ACCURACY OF MAGNETIC RESONANCE IMAGING  IN  CARCINOMA OF CERVIX TAKING HISTOPATHOLOGY AS GOLD STANDARD.

Sumera Shahbaz

DIAGNOSTIC ACCURACY OF MAGNETIC RESONANCE IMAGING IN CARCINOMA OF CERVIX TAKING HISTOPATHOLOGY AS GOLD STANDARD.

Sumera Shahbaz

Abstract

ABSTRACT

Introduction: Cervical cancer is one of leading cause of death among deaths due to cancer in women in the developing world. MRI is comparatively a newer modality in evaluation in the diagnosis of the carcinoma of the cervix so its use is likely to result in better prognosis of the patient. In comparison with histopathology, sensitivity and specificity of MRI may be determined in a public sector hospital of Metropolitan city which may be the true indicator of disease in our society.

Objective: To determine the accuracy of magnetic resonance imaging in diagnosis of the carcinoma of cervix taking histopathology as gold standard

Methods: This prospective Study was carried out in Department of Radiology, Jinnah Postgraduate Medical Centre Karachi from December 12, 2017 to January 21,2019.

305 patients fulfilling inclusion criteria were selected. The MRI scan of pelvis of these selected patients was performed.

Results: Mean (±SD) age was 42.4 (±7.1) years. Irregular vaginal bleeding was the most common clinical presentation of carcinoma of cervix found in 192 (62.9%). Sensitivity, specificity, positive predictive value and negative predictive value of MRI were 80%, 76.9%, 82.4% and 74.1% respectively. Diagnostic accuracy of magnetic resonance imaging was 78.7%.

Conclusion: High Sensitivity, specificity, and diagnostic accuracy of magnetic resonance imaging (MRI) in carcinoma of cervix makes preoperative MRI highly recommendable for work up and to determine the treatment strategy.

Key Words: Carcinoma of cervix, MRI, Histopathology, vaginal bleeding, CIN

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