Humaira Anjum, Hussain Ahmad, Mahnoor Rehman, Hina Gul



Background: Interstitial Lung Diseases (ILDs) are a group of respiratory disorders, usually chronic and progressive in nature, primarily affecting the lung parenchyma leading to reduced gas exchange. The frequency of its subtypes is variable in different regions.

Objective: To determine the prevalence of ILD subtypes in our set up on the basis of HRCT.

Materials and Methods: This was a retrospective observational study conducted at Radiology Department of Khyber Teaching Hospital Peshawar from 1st July 2014 till 30th June 2019. All HRCTs done during these five years were included for assessment of different subtypes of ILD. Scans with diagnosis other than ILD were excluded. The subtypes of ILD included were idiopathic Pulmonary Fibrosis (IPF), Non Specific Interstitial Pneumonia (NSIP), Hypersensitivity Pneumonitis (HP), Sarcoidosis, Connective Tissue Disease related ILD (CTD-ILD) and others. Patient’s age, gender and ILD subtypes were recorded in a Proforma. Data was analyzed via spss 19. Results were presented as graphs.

Results: Of the 632 scans reviewed, 171(27%) met the inclusion criteria. The mean age of patients was 51.5±18.9 years and 89 (56.9%) of the patients were females. The most common Subtype of ILD was IPF 28.16 %(n=49), followed by NSIP 25.29% (n=44), HP 13.79%(n=24), CTD-ILD 9.77%(n=17), and Sarcoidosis 7.47%(n=13). Other ILDs collectively constituted 15% of the subtypes. Conclusion: IPF was found to be the most common ILD, followed by NSIP, HP, CTD-ILD and sarcoidosis. Multidisciplinary approach and larger multicenter studies are required for better understanding of its etiology and management.

Key words: idiopathic pulmonary fibrosis, idiopathic interstitial pneumonia, hypersensitivity pneumonitis, Sarcoidosis, connective tissue disease.

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