Dr Ayesha Tareen, Dr Muhammad Omer Aamir, Dr Syed Naseer Ahmed, Dr Javed Anwar, Dr Sami Ullah Khan, Dr sadia Dilsahad, Dr Palwasha Gul, Dr Khalid shakeel Baber, Dr Baber Khan


BACKGROUND: Ultrasound is the most broadly performed procedure in the thyroid gland screening. It has easy performance and cost effectiveness in determining the size and number of nodules. The aim of this study was to determine the diagnostic accuracy of ultrasonography in differentiating benign and malignant thyroid nodules, taking histopathological findings of FNAC as gold standard. MATERIAL AND METHODS: This Descriptive, cross-sectional was conducted from 25th July 2018 to 24th January 2019 in the Department of Radiology, Combined Military Hospital, Quetta. A total of 142 patients with thyroid nodule of any size and duration >3 months, age >15 years & either gender were included. All the patients underwent grey scale ultrasonography. Findings were correlated with FNAC report. RESULTS: The data were analyzed and quantitative metric like sensitivity (Sn= 93.15%), specificity (Sp = 89.86%), positive predictive value (PPV = 90.67%), negative predictive value (NPV = 92.54%) and diagnostic accuracy (Acc = 91.55%) of ultrasonography in differentiating benign and malignant thyroid nodules were calculated taking FNAC as gold standard. CONCLUSIONS: This study concluded that ultrasound is the non-invasive modality of choice with high diagnostic accuracy in diagnosing malignant thyroid nodules.


Keywords: Thyroid cancer, ultrasound, sensitivity.

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