Dr. Shahmeer Khan, Dr. Fahd Hamid Khan, Prof. Zafar Sajjad, Dr. Ayesha Shoukat, Dr. Fatima Mubarak


The perineural space is a potential space between neural elements and the epineural sheath in a nerve. This can serve as a conduit for the spread of malignant, inflammatory and infective head and neck pathologies to a location distant from their source of origin. Imaging techniques, including contrast-enhanced MRI and PET-CT scans play an important role in the identification of this entity. This is a series of three cases of head and neck pathologies with perineural intracranial extension of disease, with emphasis on anatomy and imaging features of nerve involvement.

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