Farrukh Nadeem, Mehwish Anwar, Asad Khan, Koukab Javed


OBJECTIVE:  To determine diagnostic accuracy of power Doppler ultrasonography in evaluation of solid breast mass lesions for malignancy keeping histopathology as gold standard.

MATERIALS AND METHODS:  The study was done in radiology department combined military hospital Rawalpindi from 01July 2018 to 30June 2019 using  Xario200 Toshiba ultrasound machine with high frequency probe. Those patients with palpable breast mass referred to radiology department for breast ultrasonography fulfilling inclusion criteria were registered in the study. Informed consent was taken from all patients. The power Doppler ultrasound of breast of all patients were performed and findings were analyzed by two consultant radiologist in double blind  interpretation. All included patients followed a trucut biopsy of breast mass. Power Doppler and histopathological findings were noted on a dedicated performa. At the end, data was put in2x2 table to calculate statistical values.

RESULTS:   Total 202 patients were studied during the study period. Age range of patients in this study was from 30-60 years. Power Doppler ultrasound findings supported the diagnosis of malignant breast mass lesions in 130 patients. Among which ,113were  true positive and 17 were false positive on histopathology.  Among 72 power Doppler negative patients for malignancy, 14 were false negative whereas 58 were true negative on histopathology.  The sensitivity, specificity, diagnostic accuracy, positive predictive value and negative predictive value  of power Doppler ultrasound in predicting malignancy in evaluation of solid breast lesions was 88.97%, 77.33%, 84.65%, 86.92% and 80.55% respectively.

CONCLUSION:  The peculiar vascular pattern in malignant breast masses are very effectively detected by power Doppler ultrasound. So it should be included as integral part of every sonomamographic  examination of solid breast lesions.

KEYWORDS :  Breast mass, power Doppler ultrasound, hypervascularity, penetrating vessels.  

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