PET IMAGING OF ER AND PR RECEPTORS IN BREAST CANCER: NEW INSIGHT
Abstract
In breast cancer (BC) steroid hormone receptors like Estrogen Receptor (ER) and Progesterone Receptor (PR) are the established prognostic and predictive markers. These receptors act as ligand-activated nuclear transcription factor which regulate the gene expression. ER and PR are expressed in about 75% of BC and their presence is used to predict prognosis and therapeutic response.
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