PET IMAGING OF ER AND PR RECEPTORS IN BREAST CANCER: NEW INSIGHT

Maseeh uz Zaman, Nosheen Fatima, Wajeeha Shahid, Sidra Zaman, Areeba Zaman, Unaiza Zaman

Abstract


In breast cancer (BC) steroid hormone receptors like Estrogen Receptor (ER) and Progesterone Receptor (PR) are the established prognostic and predictive markers. These receptors act as ligand-activated nuclear transcription factor which regulate the gene expression. ER and PR are expressed in about 75% of BC and their presence is used to predict prognosis and therapeutic response.


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