RHINO-ORBITAL MUCORMYCOSIS IN A COVID-19 PATIENT IN PAKISTAN : CASE REPORT
Abstract
Abstract:
Severe acute respiratory syndrome coronavirus (SARS-CoV-2) or 2019 novel coronavirus (2019-nCoV) was first reported in China, which spread all over the world causing a pandemic. Opportunistic infections are very commonly seen with Covid-19 infection. Patients with comorbidities are at higher risk. We report a case of an elderly male who was diagnosed with Covid-19 on HRCT and PCR. Non-contrast MR brain and non-contrast CT paranasal sinuses showed pansinusitis with internal differential high densities and suggestion of fungal infection was given. Functional Endoscopic Sinus Surgery (FESS) was performed followed by amphotericin B lavage. Postoperative contrast-enhanced MRI brain showed interval reduction in the enhancing mucosal thickening with abnormal signal intensity signal extending into bilateral orbital apices. Thus, post-Covid rhino-orbital mucormycosis was timely diagnosed by radio-pathological aid. Despite appropriate intervention including antibiotics cover and surgical debridement, the disease progressed into orbits, due to multiple factors like immunocompromised status, comorbidities or use of excessive steroid therapy in treating Covid-19 infection. Post Covid-19 infection, rhino-orbital mucormycosis presentation is very rare and one of its kind case reported in Pakistan.
Keywords: Mucormycosis, Orbit, Covid-19, Fungal infections, Case report, Pakistan.
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