DIAGNOSTIC ACCURACY OF MULTISLICE COMPUTED TOMOGRAPHY IN BONY INVASION OF THE SQUAMOUS CELL CARCINOMA OF ORAL CAVITY

Abstract

INTRODUCTION

Oral carcinoma is one of the greatest health problems globally with increasing prevalence. It is the second most common malignancy in both genders in Pakistan. They are responsible for approximately 200,000 deaths per year worldwide. The most common malignancy of the oral cavity is squamous cell carcinoma (SCC). In a recent study bony invasion by squamous cell carcinoma is found to be 53.3% in mandible, 15.5% in maxilla and 4.4% in both. One of the important roles of imaging is to detect bony invasion of oral SCC. The management of these patients depend upon the bony invasion.

This aim of this study is to evaluate the diagnostic accuracy of the computed tomography in detecting the bony invasion of oral squamous cell carcinoma. Early detection is of utmost important in planning the treatment regimen to reduce the risk of distant metastasis and consequent morbidity and mortality.

MATERIAL AND METHODS:

This was a cross sectional study conducted at the Department of Diagnostic Radiology, Ziauddin medical University and hospital. 211 patients were included in our study who has oral squamous cell carcinoma referred to our radiology department for imaging. Multislice Computed Tomography was done, and assessment was made for bone invasion of the tumor. Histopathology was done as the gold standard. Sensitivity & Specificity were calculated by comparing the results with histopathology.

RESULTS:

The sensitivity and specificity of the computed tomography for the detection of bone invasion were 97.11% and 89.7% respectively.

CONCLUSION:

Mulltislice Computed Tomography is a noninvasive imaging modality in early detection of bony invasion of oral squamous cell carcinoma with high accuracy. CT reconstruction with bone algorithm is accurate technique in detection of bony invasion.

KEYWORDS: Multislice Computed Tomography, Oral carcinoma, Squamous cell carcinoma, Bony invasion.