MAGNETIC RESONANCE IMAGING FINDINGS OF GRANULOSA CELL TUMOR OF THE OVARY

Abstract

Ovarian granulosa cell tumor (GCT) is a low-grade malignant tumor, and the most common functioning ovarian tumor.1,2 For most patients, surgery alone is sufficient primary therapy.2 However, GCT is potentially aggressive. Between10-50% of patients develop recurrences,1 and when GCT does recur, it can progress quite rapidly.2 The most important prognostic factor is tumor stage1,3 and tumor size has also been known to influence prognosis.4 In addition, when functional most GCT are estrogenic (70%), but rarely, androgenic effects may be present as well.1,3-6 When the tumor is functional, a typical endometrial effect is cystic hyperplasia usually exhibiting some degree of precancerous atypia, and carcinoma occurs in less than 5% of cases.2-5 Evaluation of the uterine endometrium is also important.7