LYMPHOCYTIC INFUNDIBULO-NEURO HYPOPHYSITIS: A RARE CAUSE OF DIABETES INSIPIDUS

Abstract

A 69 years old female with polydipsia, polyuria and intermittent headache for 6 months was admitted to hospital due to intractable symptoms for last 3 months. On Admission, physical examination, blood glucose level, pituitary and thyroid hormones level were with in normal limits. Urine Specific gravity was slightly decreased. MRI showed slight enlargement of sella turcica, with uniform flattening of floor, pituitary showed uniform, mild enlargement (1.1cmX1.5cmX1.2cm), isointense to white mater in T1WI with loss of normal “bright spots” of posterior pituitary, heterogeneous signal with low intensity posteriorly in T2WI and intense homogeneous enhancement with “dural tail” in T1WI with Gadolinium. Pituitary stalk was slightly thickened but undisplaced. The lesion was diagnosed as pituitary adenoma and underwent transsphenoidal excision of pituitary.