DIAGNOSTIC ACCURACY OF MAGNETIC RESONANCE CHOLANGIOPANCREATOGRAPHY FOR DETECTION OF CHOLEDOCHOLITHIASIS IN OBSTRUCTIVE JAUNDICE PATIENTS TAKING SURGICAL FINDINGS AS GOLD STANDARD

Abstract

ABSTRACT

Introduction;

 Magnetic resonance imaging (MRCP) has been used as non-invasive technique for diagnosing common bile duct stones. Rationale of this study was to gather data about MRCP in our settings to develop our local guidelines for early and non-invasive diagnosis of common bile duct stones. This will help in early initiation of definitive therapy in these patients.

Objectives;

To determine diagnostic accuracy of MRCP for detection of choledocholithiasis in obstructive jaundice patients taking surgical findings as gold standard.

Materials and methods;

It is a Cross-sectional (validation) study of six months duration. Study was performed in department of Diagnostic Radiology. MRCP of 125 patients of either gender with age between 20-60 years who had clinical and laboratory evidence of obstructive jaundice, was performed. MRI machine of 1.5Tesla was used. MRCP results were correlated with surgical findings. Sensitivity, specificity, PPV, NPV and overall accuracy was calculated.

Results;

36.0% (n=45) patients were males and 64.0% (n=80) were females. 72.0 % (n=90) of patients were positive on MRCP and 74.4% (n=93) of patients were positive on surgery. Sensitivity, specificity, PPV, NPV and accuracy were found to be 94.6%, 93.8%, 97.8%, 85.7% and 94.4% respectively.

Conclusions:

MRCP allows non-invasive detection of common bile duct stones with excellent accuracy.

KEY WORDS:

Choledocholithiasis, obstructive jaundice, MRCP.