Diagnostic accuracy of Doppler Ultrasound in Diagnosis of Malignant Cervical Lymphadenopathy
Abstract
Setting: Department of Radiology Allied Hospital, Faisalabad. Period: From August 2014 to June 2015, Patientsand method:A total of 213 patients with enlarged cervical lymph nodes were recruited in this study and underwent both Doppler ultrasound and histopathological examination. Doppler Ultrasound of cervical lymph nodes was done with GE logic 5- machine by using a linear transducer of 7MHz. Lymph nodes were characterized into malignant lymphnodes i.e nodes which are round,show peripheral blood flow,sharp margins,RI greater than 0.7 and PI greater than 1.5 and nonmalignant lymphnodes i.e nodes which are oval,show central blood flow,indistinct margins,RI lesser than 0.7 and PI lesser than 1.5.Results:Mean age of the patients was 33.1±8.3 years. There were 139 males and 74 females were included in this study. There were 183 malignant cases on Doppler ultrasound and 30 non-malignant while 176 were malignant on histopathology and 37 were non-malignant. Sensitivity, specificity, diagnostic accuracy, positive predictive value and negative predictive values were 98.8%, 75.6%, 94.8%, 95.0% and 93.3%, respectively.
Conclusion:Doppler ultrasound is a useful imaging modality in malignant cervical lymphadenopathy. Ultrasonography is an easy, reproducible, non-invasive, no risk procedure, radiation free imaging modality to examine the cervical lymphadenopathy.
Key wordsDoppler ultrasound, Cervical lymph nodes, Malignancy
Full Text:
PDFReferences
References
Seethala RR. Current state of neck dissection in the United States. Head Neck Pathol 2009;3:238-45.
Zahir ST,Azmi A.Histopathologic findings of lymph node biopsy cases in comparison with clinical features.Pak J Med Sci 2009;25:728-33.
Ahuja AT, Ying M, Ho SY, Antonio G,Lee YP,King AD,et al.Ultrasound of malignant cervical lymph nodes.Cancer Imaging 2008;8:48-56.
Khanna R, Sharma AD, Khanna S,Kumar M, Shukla RC. Usefulness of ultrasonography for evaluation of cervical lymphadenopathy.World J Surg Oncol 2011;9:29.
Choi EC, Moon WJ, Lim YC. Tuberculous cervical lymphadenitis mimicking metastatic lymph nodes from papillary thyroid carcinoma. Br J Radiol 2009;82e:208-11.
Dangore –Khasbage S,Degwekar SS, Bhowate RR, Banode PJ,Bhake A. Utility of colour Doppler ultrasound in evaluating the status of cervical lymph nodes in oral cancer. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009;108:255-63.
Qasmi SA, Kiani F, Malik AI, Salamatullah J, Farooq MO, Abbasi MA. Cervical lymphadenopathy:a common diagnostic dilemma. J Surg Pak2012;17:76-80.
Alam K, Maheshwari V, Haider N, Siddiqui FA, Jain A, Khan AH. Fine needle aspiration cytology (FNAC), a handy tool for metastatic lymphadenopathy. The internet J Pathol2010;10.
Russell RCG, Norman S, Christopher, ‘Bailey & Love’s Short practice of surgery’, 24th ed London: Hodder Arnold, 2004. p. 936-8.
Mahazer H, Sharifkashani SH, Sharifian H, ‘Triplex ultrasonographic assessment of cervical lymph nodes. Acta Medica Iranica 2004;42:441-4.
Gul E. Ultrasound of superficial lymph nodes. Eur J Radiol 2006;58:345-9.
Choi MY, Lee JW, Jang KJ. Distinction between benign and malignant causes of cervical, axillary, and inguinal lymphadenopathy: value of doppler spectral waveform analysis. Am J Roentgenol 1995;165:981–4.
Steinkamp HJ,Mueffelmann M,Böck JC,Thiel T,Kenzel P,Felix R.Differential diagnosis of lymph node lesions: a semiquantitative approach with colour Doppler ultrasound.Br J Radiol1998;71:828-33.
Chang DB. Differentiation of benign and malignant cervical lymph nodes with color Doppler sonography. Am J Roentgenol 1994;162:965–8.
Refbacks
- There are currently no refbacks.
© Copyright PJR 2008- |