BISPHOSPHONATE INDUCED ATYPICAL PROXIMAL FEMORAL FRACTURE: “DOUBLE EDGE DAGGER” RADIOLOGICAL AND SCINTIGRAPHY FINDINGS

Authors

  • Nosheen Fatima Dept. of Radiology, Aga Khan University Hospital, Karachi, Pakistan
  • Areeba Zaman Dept. of Medicine, Ruth Pfau Hospital, Karachi, Pakistan
  • Sidra Zaman Student MBBS, Dow Medical College, Dow University of Health Sciences (DUHS), Karachi, Pakistan
  • Anamta Zaman Student BDS, Liaquat College of Medicine and Dentistry, Karachi, Pakistan.
  • Unaiza Zaman Dept. of Medicine, SUNNY Downstate Hospital, New York, USA
  • Maseeh uz Zaman Aga Khan University Hospital Karachi, Pakistan

Abstract

Bisphosphonate therapy has been an established and effective therapeutic option to prevent osteoporotic hip and other fractures but undeniable plethora of side effects ranging from esophagitis, iritis, jaw necrosis and atypical femoral fractures. AFFs are not very common but present pain, incomplete insufficiency fracture to complete fracture. These fractures have higher tendency of delayed union or non-union due to bisphosphonate induced reduced bone remodeling. So beyond any doubt benefits of bisphosphonate outweigh its risks but one should not forget it is a “Double Edge Dagger”.

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Published

01-10-2021

How to Cite

Fatima, N., Zaman, A., Zaman, S., Zaman, A., Zaman, U., & uz Zaman, M. (2021). BISPHOSPHONATE INDUCED ATYPICAL PROXIMAL FEMORAL FRACTURE: “DOUBLE EDGE DAGGER” RADIOLOGICAL AND SCINTIGRAPHY FINDINGS. Pakistan Journal of Radiology, 31(3). Retrieved from https://www.pakjr.com/index.php/PJR/article/view/1432

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Section

Review Article